{"id":7356,"date":"2022-01-30T18:11:00","date_gmt":"2022-01-30T16:11:00","guid":{"rendered":"https:\/\/www.marketingensales.com\/adoa?p=7356"},"modified":"2023-07-01T17:18:56","modified_gmt":"2023-07-01T15:18:56","slug":"de-weg-naar-de-behandeling-8","status":"publish","type":"post","link":"https:\/\/www.marketingensales.com\/adoa\/de-weg-naar-de-behandeling\/de-weg-naar-de-behandeling-8","title":{"rendered":"De weg naar behandeling 8","gt_translate_keys":[{"key":"rendered","format":"text"}]},"content":{"rendered":"
Lees Voor<\/span><\/span><\/span><\/span><\/a><\/div>
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De weg naar behandeling 8<\/h2>\t\t\t\t
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Eind 2021 stuurde \u00e9\u00e9n van onze contactpersonen bij Stoke Therapeutics ons hun financi\u00eble resultaten en bedrijfsupdates toe. Hierin staat o.a. (vertaald vanaf hun pagina):<\/p>\n

Het bedrijf heeft STK-002 genomineerd als klinische kandidaat voor de behandeling van ADOA, een ernstige en progressieve aandoening van de oogzenuw. Er zijn momenteel geen goedgekeurde behandelingen voor ADOA, dat voornamelijk wordt veroorzaakt door functieverliesmutaties in het OPA1-gen, wat resulteert in 50% OPA1-eiwitexpressie en ziektemanifestatie. STK-002, een gepatenteerd antisense-oligonucleotide (ASO), is ontworpen om de OPA1-eiwitexpressie te verhogen door gebruik te maken van de niet-mutante (wildtype) kopie van het OPA1-gen. Op basis van tot nu toe gegenereerde preklinische gegevens is het bedrijf van mening dat STK-002 het potentieel heeft om een ziekte modificerende therapie te zijn voor mensen die leven met ADOA.<\/em><\/p>\n

Het gehele stuk is\u00a0hier<\/strong>\u00a0te lezen.<\/a><\/p>\n\t\t\t\t<\/div>\n\t\t\t<\/div><\/div>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>","protected":false,"gt_translate_keys":[{"key":"rendered","format":"html"}]},"excerpt":{"rendered":"

<\/p>\n

Lees Voor<\/span><\/span><\/span><\/span><\/a><\/div>\n
De weg naar behandeling 8 Eind 2021 stuurde \u00e9\u00e9n van onze contactpersonen bij Stoke Therapeutics ons hun financi\u00eble resultaten en bedrijfsupdates toe. Hierin staat o.a. (vertaald vanaf hun pagina): Het bedrijf heeft STK-002 genomineerd als klinische kandidaat voor de behandeling van ADOA, een ernstige en progressieve aandoening van de oogzenuw. Er zijn momenteel […]<\/div>\n","protected":false,"gt_translate_keys":[{"key":"rendered","format":"html"}]},"author":4,"featured_media":9027,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_eb_attr":""},"categories":[143],"tags":[],"yoast_head":"\nDe weg naar behandeling 8 | Cure ADOA Foundation<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.marketingensales.com\/adoa\/de-weg-naar-de-behandeling\/de-weg-naar-de-behandeling-8\" \/>\n<meta property=\"og:locale\" content=\"nl_NL\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"De weg naar behandeling 8 | Cure ADOA Foundation\" \/>\n<meta property=\"og:description\" content=\"Lees Voor De weg naar behandeling 8 Eind 2021 stuurde \u00e9\u00e9n van onze contactpersonen bij Stoke Therapeutics ons hun financi\u00eble resultaten en bedrijfsupdates toe. Hierin staat o.a. (vertaald vanaf hun pagina): Het bedrijf heeft STK-002 genomineerd als klinische kandidaat voor de behandeling van ADOA, een ernstige en progressieve aandoening van de oogzenuw. 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